The Great Lakes’ ___ Locks

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Possible Answers: SOO.

Random information on the term “SOO”:
Sault Ste. Marie (/suː seɪnt məriː/ “Soo Saint Marie”) is a city on the St. Marys River in Algoma District, Ontario, Canada. It is the third largest city in Northern Ontario, after Sudbury and Thunder Bay.
Taken from Wikipedia