Now we are looking on the crossword clue: Medical research grail.
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Possible Answers: CURE.
Random information on the term “CURE”:
Cure (キュア, Kyua?) is a 1997 Japanese thriller film directed by Kiyoshi Kurosawa, starring Koji Yakusho, Masato Hagiwara, Tsuyoshi Ujiki and Anna Nakagawa.
Taken from Wikipedia