Now we are looking on the crossword clue: Cool, in hip-hop slang.
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Possible Answers: DEF.
Random information on the term “DEF”:
Deferoxamine (also known as desferrioxamine B, desferoxamine B, DFO-B, DFOA, DFB or desferal) is a bacterial siderophore produced by the actinobacteria Streptomyces pilosus. It has medical applications as a chelating agent used to remove excess iron from the body. The mesylate salt of DFO-B is commercially available.
Taken from Wikipedia