Broken-heart symptom

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Now we are looking on the crossword clue: Broken-heart symptom.
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Possible Answers: ACHE.

Random information on “Acetylcholinesterase”:
Acetylcholinesterase, also known as AChE or acetylhydrolase, is a serine protease that hydrolyzes the neurotransmitter acetylcholine. AChE is found at mainly neuromuscular junctions and cholinergic brain synapses, where its activity serves to terminate synaptic transmission. It belongs to carboxylesterase family of enzymes.
Taken from Wikipedia