Bestselling game set in a deserted world

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Possible Answers: MYST.

Random information on the term “MYST”:

The Myst series of adventure computer games deal with the events following the player’s discovery of a mysterious book describing an island known as Myst. The book is no ordinary volume; it is a linking book, which serves as a portal to the world it describes. The player is transported to Myst Island, and must unravel the world’s puzzles in order to return home. Myst was a commercial and critical success upon release, and spawned four sequels—Riven, Exile, Revelation and End of Ages— as well as several spinoffs and adaptations.
Taken from Wikipedia